Database of New Zealand mental health research
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A randomized control trial investigating the impact of micronutrients on behaviour and mood in adults with ADHD
Investigator(s) / AuthorsDr Anna Boggis, Sarah Anticich, Rachel Harrison, Jeni Johnstone
| Principal contact | |
|---|---|
| Name | Dr Julia Rucklidge |
| Julia.rucklidge@canterbury.ac.nz | |
| The research | |
| Summary | Attention-Deficit/Hyperactivity Disorder (ADHD) is a neurobehavioural developmental disorder that affects 3-5% of the population. Pilot data, using a micronutrient formula (vitamins and minerals) in an 8-week open-label design, found that ADHD adults showed improved ADHD symptoms, emotional lability, and neurocognitive functioning. |
| Objectives | We propose to extend this research using an 8-week double-blind randomised placebo-controlled design with an 8-week open-label extension with 30 participants per group to study how micronutrients compare with a placebo in the treatment of adult ADHD. The results have the potential to change our way of conceptualizing this chronic condition offering an alternative neurochemical explanation for symptoms. The aim of this study is to assess the efficacy of a micronutrient formula (EMPowerplus or EMP+) compared with placebo in 60 medication-free adults with ADHD and mood instability, in improving overall symptomatology as well as neurocognitive functioning from baseline to the end of 8 weeks of therapy, as assessed under randomized and fully blinded conditions. We also plan to assess the safety of EMP+ compared with placebo and to assess the longer term impact of EMP+ under an 8-week open-label extension. |
| Study design | This current study aims to extend this research using an 8-week double-blind randomised placebo-controlled design with an 8-week open-label extension with 30 participants per group (age range 16-45), in order to determine how EMP+ compares with a placebo in the treatment of ADHD in improving overall psychiatric symptomatology and neurocognitive functioning. |
| Methods | Clinical Trial |
| Results | |
| Conclusions | |
| Key Descriptors | Intervention/Treatment |
| Disciplines | Multi disciplinary, Psychiatry, Psychology |
| Settings | Outpatient |
| Diagnostic Categories | Developmental Disorders, Mood & Affective Disorders |
| Populations | General Population |
| Other Keywords | ADHD, attention deficit hyperactivity disorder, micronutrients, vitamins, minerals |
| Ethics approval | Yes |
| Academic led | Yes |
| Service led | No |
| How were service users involved | Participants of the research |
| Publication in peer review journal | Yes |
| Supporting information | |
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Page last updated: 7 November 2008